Tuesday, July 08, 2014

A microfluidic method to synthesize transferrin-lipid nanoparticles loaded with siRNA LOR-1284 for therapy of acute myeloid leukemia




Nanoscale , 2014, Advance Article

DOI: 10.1039/C4NR01510J, Paper

Zhaogang Yang, Bo Yu, Jing Zhu, Xiaomeng Huang, Jing Xie, Songlin Xu, Xiaojuan Yang, Xinmei Wang, Bryant C. Yung, L. James Lee, Robert J. Lee, Lesheng Teng

Transferrin (Tf) conjugated lipid nanoparticles were synthesized by a microfluidic hydrodynamic focusing (MHF) method for targeted delivery of the nanoparticles into acute myeloid leukemia cells.

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