Wednesday, July 02, 2014

The use of pH-sensitive functional selenium nanoparticles shows enhanced in vivo VEGF-siRNA silencing and fluorescence imaging




Nanoscale , 2014, Advance Article

DOI: 10.1039/C4NR02423K, Paper

Qianqian Yu, Yanan Liu, Chengwen Cao, Fangling Le, Xiuying Qin, Dongdong Sun, Jie Liu

The pH-sensitive delivery system G2/PAH-Cit/SeNPs@siRNA enhances anti-tumor effects through VEGF gene silencing and reduces angiogenesis, with no side effects in organs.

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