Thursday, July 17, 2014

ZEB1 knockdown mediated using polypeptide cationic micelles inhibits metastasis and effects sensitization to a chemotherapeutic drug for cancer therapy




Nanoscale , 2014, Advance Article

DOI: 10.1039/C4NR01518E, Paper

Shengtao Fang, Lei Wu, Mingxing Li, Huqiang Yi, Guanhui Gao, Zonghai Sheng, Ping Gong, Yifan Ma, Lintao Cai

We demonstrated the use of a multifunctional nanocarrier to overcome metastasis and drug resistance by delivering ZEB1 siRNA or co-delivering ZEB1 siRNA and DOX.

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