Thursday, August 14, 2014

Enhanced antitumor activity and mechanism of biodegradable polymeric micelles-encapsulated chetomin on both transgenic zebrafish and mouse models

Nanoscale , 2014, Accepted Manuscript

DOI: 10.1039/C4NR02978J, Paper

Qinjie Wu, Guoyou Li, Senyi Deng, Liang Ouyang, Ling Li, Lei Liu, Na Luo, Xiangrong Song, Gu He, Changyang Gong, Yuquan Wei

Chetomin is a promising molecule with anti-tumor activities in the epipolythiodioxopiperazines family of fungal secondary metabolites; however, strong hydrophobicity limited its further applications. In this work, chetomin was encapsulated into...

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