Thursday, October 23, 2014

Entropy-enthalpy compensation at the single protein level: pH sensing in the bacterial channel OmpF.

Nanoscale , 2014, Accepted Manuscript

DOI: 10.1039/C4NR03811H, Paper

Antonio Alcaraz, Maria Queralt-Martin, Carmina Verdia-Baguena, Vicente M Aguilella, Salvador Mafe

The pH sensing mechanism of OmpF channel operates via ligand modification: increasing acidity induces the replacement of cations with protons in critical binding sites decreasing the channel conductance. Aside from...

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