Monday, November 24, 2014

PSMA-mediated endosome escape-accelerating polymeric micelles for targeted therapy of prostate cancer and the real time tracing of their intracellular trafficking




Nanoscale , 2015, Advance Article

DOI: 10.1039/C4NR05738D, Paper

Yajie Gao, Yanfang Li, Yushu Li, Lan Yuan, Yanxia Zhou, Jinwen Li, Lei Zhao, Chao Zhang, Xinru Li, Yan Liu

To ensure that anticancer drugs could be delivered to tumor region and rapidly escape from endo/lysosomes, YPSMA-1-modified pH-sensitive polymeric micelles were designed and fabricated for targeted therapy of tumors.

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