Targeting FR-expressing cells in ovarian cancer with Fab-functionalized nanoparticles: a full study to provide the proof of principle from in vitro to in vivo

Nanoscale , 2014, Accepted Manuscript

DOI: 10.1039/C4NR04426F, Paper

Alessandra Quarta, Davide Bernareggi, Fabio Benigni, Elena Luison, Giuseppe Nano, Simone Nitti, Candida Cesta, Luciano Di Ciccio, Silvana Canevari, Teresa Pellegrino, Mariangela Figini

Efficient targeting in tumor therapies is still an open issue: systemic biodistribution and poor specific accumulation of drugs weaken efficacy of treatments. Engineered nanoparticles are expected to bring benefits allowing...

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