Monday, November 17, 2014

Topical Gene Silencing by iontophoretic delivery of antisense oligonucleotide-dendrimer nanocomplex: Proof of concept in a skin cancer mouse model

Nanoscale , 2014, Accepted Manuscript

DOI: 10.1039/C4NR05241B, Paper

Venkata Vamsi K. Venuganti, Manju Saraswathy, Chandradhar Dwivedi, Radhey Kaushik, Omathanu Perumal

The study was aimed at investigating the feasibility of using poly (amidoamine) (PAMAM) dendrimer as a carrier for topical iontophoretic delivery of antisense oligonucleotide (ASO). Bcl-2, an anti-apoptotic protein implicated...

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