Biodegradable polymeric micelles encapsulated JK184 suppress tumor growth through inhibiting Hedgehog signaling pathway

Nanoscale , 2014, Accepted Manuscript

DOI: 10.1039/C4NR06300G, Paper

Nannan Zhang, Shichang Liu, Ning Wang, Senyi Deng, Linjiang Song, Qinjie Wu, Lei Liu, Weijun Su, Yuquan Wei, Yongmei Xie, Changyang Gong

JK184 could specially inhibit Gli in Hedgehog (Hh) pathway, which showed great promise in cancer therapeutics. For developing aqueous formulation and improving anti-tumor activity of JK184, we prepared JK184 encapsulated...

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