Monday, December 01, 2014

Investigations in dendrimer space reveal solid and liquid tumor growth-inhibition by original phosphorus-based dendrimers and corresponding monomers and dendrons with ethacrynic acid motifs

Nanoscale , 2014, Accepted Manuscript

DOI: 10.1039/C4NR05983B, Paper

Nabil El Brahmi, Serge Mignani, Joachim Caron, Said El Kazzouli, Mosto Bousmina, Anne-Marie Caminade, Thierry Cresteil, Jean-Pierre Majoral

The well-known reactive diuretic Ethacrynic acid (EA, Edecrin), showing low antiproliferative activities, was chemically modified and grafted on phosphorus dendrimers and corresponding simple branched phosphorus dendrons-like affording original nanodevices showing...

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