Monday, January 05, 2015

Galactose-functionalized Multi-responsive Nanogels for Hepatoma-targeted Drug Delivery

Nanoscale , 2015, Accepted Manuscript

DOI: 10.1039/C4NR06714B, Paper

Shaofeng Lou, Shan Gao, Weiwei Wang, Mingming Zhang, Ju Zhang, Chun Wang, Chen Li, Deling Kong, Qiang Zhao

We report here a hepatoma-targeting multi-responsive biodegradable crosslinked nanogel, poly(6-O-vinyladipoyl-D-galactose-ss-N-vinylcaprolactam-ss-Methacrylic acid) P(ODGal-VCL-MAA), using a combination of enzymatic transesteriļ¬cation and emulsion copolymerization for intracellular drug delivery. The nanogel exhibited redox, pH...

The content of this RSS Feed (c) The Royal Society of Chemistry





Click for full article

No comments:

Post a Comment