Tuesday, January 06, 2015

Protein Denaturation at Single-molecule Level: The Effect of Nonpolar Environments and Its Implications to the Unfolding Mechanism by Proteases

Nanoscale , 2015, Accepted Manuscript

DOI: 10.1039/C4NR07140A, Paper

Bo Cheng, Shaogui Wu, Shixin Liu, Piere Rodriguez, Jin Yu, Shuxun Cui

Most proteins are typically folded into predetermined three-dimensional structures in the aqueous cellular environment. However, proteins can be exposed to a nonpolar environment under certain conditions, such as inside the...

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