Monday, March 02, 2015

Diameter-dependent release of a cisplatin pro-drug from small and large functionalized carbon nanotubes




Nanoscale , 2015, Advance Article

DOI: 10.1039/C5NR00220F, Paper

Laura Muzi, Cecilia Menard-Moyon, Julie Russier, Jian Li, Chee Fei Chin, Wee Han Ang, Giorgia Pastorin, Gianfranco Risuleo, Alberto Bianco

A Pt(IV) prodrug was encapsulated inside two types of multi-walled cabon nanotubes with different diameter. Upon cell internalization, the drug is released and exerts its cytotoxic function in a diameter-dependent manner.

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