Wednesday, April 08, 2015

Functionalized iron oxide nanoparticles for controlling the movement of immune cells




Nanoscale , 2015, Advance Article

DOI: 10.1039/C3NR04421A, Paper

Ethan E. White, Alex Pai, Yiming Weng, Anil K. Suresh, Desiree Van Haute, Torkom Pailevanian, Darya Alizadeh, Ali Hajimiri, Behnam Badie, Jacob M. Berlin

Coating super paramagnetic iron oxide nanoparticles with an immunostimulant, CpG oligodeoxynucleotides, dramatically increases their uptake by microglia cells. Once loaded with the nanoparticles, the microglia cells can be manipulated with magnets.

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