Thursday, April 09, 2015

Impact of anatase and rutile titanium dioxide nanoparticles on uptake carriers and efflux pumps in Caco-2 gut epithelial cells




Nanoscale , 2015, 7,7352-7360

DOI: 10.1039/C5NR00505A, Paper

M. Dorier, E. Brun, G. Veronesi, F. Barreau, K. Pernet-Gallay, C. Desvergne, T. Rabilloud, C. Carapito, N. Herlin-Boime, M. Carriere

TiO2 -NPs, both anatase and rutile, accumulate in Caco-2 cells and up-regulate a battery of nutrient transporters and efflux pumps, but do not cause overt mortality or DNA damage.

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