Friday, May 01, 2015

Low affinity binding of plasma proteins to lipid-coated quantum dots as observed by in-situ fluorescence correlation spectroscopy

Nanoscale, 2015, Accepted Manuscript
DOI: 10.1039/C5NR01694K, Communication
Yvonne Klapper, Pauline Maffre, Li Shang, Kristina N. Ekdahl, Bo Nilsson, Simon Hettler, Manuel Dries, Dagmar Gerthsen, G. Ulrich Nienhaus
Protein association to lipid-coated nanoparticles has been pursued quantitatively by using fluorescence correlation spectroscopy. For three important plasma proteins, we found extremely low binding affinities toward lipid-enwrapped quantum dots (QDs)....
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