Thursday, July 30, 2015

Magnetic field activated drug delivery using thermodegradable azo-functionalised PEG-coated core-shell mesoporous silica nanoparticles

Nanoscale, 2015, 7,13168-13172
DOI: 10.1039/C5NR03777H, Communication
P. Saint-Cricq, S. Deshayes, J. I. Zink, A. M. Kasko
Core-shell Fe3O4@SiO2 mesoporous silica nanoparticles coated with a thermodegradable polymer allowed the release of a model drug through heating caused by a high frequency oscillating magnetic field. The polymer was made of poly(ethylene glycol) (PEG) functionalised with azo bonds that break with an elevation of temperature.
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