Wednesday, August 19, 2015

An innovative pre-targeting strategy for tumor cell specific imaging and therapy

Nanoscale, 2015, Advance Article
DOI: 10.1039/C5NR03862F, Paper
Si-Yong Qin, Meng-Yun Peng, Lei Rong, Hui-Zhen Jia, Si Chen, Si-Xue Cheng, Jun Feng, Xian-Zheng Zhang
An innovative pre-targeting system based on artificial "biotinylated transferrin-avidin-biotinylated peptide" interaction was established, which was achievable for the tumor cell fluorescence imaging and thereafter targeting therapy from biotinylated pro-apoptotic peptide nano-vesicles.
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