Friday, August 21, 2015

Tumor pHe-triggered charge-reversal and redox-responsive nanoparticles for docetaxel delivery in hepatocellular carcinoma treatment

Nanoscale, 2015, Accepted Manuscript
DOI: 10.1039/C5NR04612B, Paper
Fengqian Chen, Jinming Zhang, Lu Wang, Yitao Wang, Meiwan Chen
The insufficient cellular uptake of nanocarriers and their slow drug release have become major obstacles for achieving satisfactory anticancer outcomes in nano-medicine therapy. Because the slightly acidic extracellular environment (pHe[approximate]6.5)...
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