Dissecting the contributions of [small beta]-hairpin tyrosine pair to the folding and stability of long-lived human ΥD-crystallins

Nanoscale , 2013, Accepted Manuscript

DOI: 10.1039/C3NR03782G, Paper

Zaixing Yang, Zhen Xia, Tien Huynh, Jonathan A King, Ruhong Zhou

Ultraviolet-radiation-induced damage to and aggregation of human lens crystallin proteins are thought to be a significant pathway to age-related cataract. The aromatic residues within the duplicated Greek key domains of...

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