A factor VIII-derived peptide enables von Willebrand factor (VWF)-binding of artificial platelet nanoconstructs without interfering with VWF-adhesion of natural platelets

Nanoscale , 2014, Advance Article

DOI: 10.1039/C3NR06400J, Paper

Hassan Haji-Valizadeh, Christa L. Modery-Pawlowski, Anirban Sen Gupta

Co-decoration of liposomal nanoconstructs with FVIII-derived VWF-binding-peptides (VBP) and active platelet-clustering fibrinogen-mimetic-peptides (FMP) allows platelet-mimetic VWF-adhesion and platelet aggregation.

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