DNA-based Detection of Mercury(II) Ions through Characteristic Current Signals in Nanopore with High Sensitivity and Selectivity

Nanoscale , 2014, Accepted Manuscript

DOI: 10.1039/C4NR02062F, Communication

Tao Zeng, Ting Li, Yuru Li, Lei Liu, Xingyong Wang, Quansheng Liu, Yuliang Zhao, Hai-Chen Wu

We report single-molecule detection of Hg²⁺ by threading a Hg²⁺ mediated DNA duplex through [small alpha]-hemolysin nanopore which generates characteristic three-level current patterns enabling unambiguous detection of Hg²⁺ . This strategy precludes...

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