The functional dissection of the plasma corona of SiO2-NPs spots Histidine Rich Glycoprotein as a major player able to hamper nanoparticles capture by macrophages

Nanoscale, 2015, Accepted Manuscript
DOI: 10.1039/C5NR05290D, Paper

Chiara Fedeli, Daniela Segat, Regina Tavano, Luigi Bubacco, Giorgia De Franceschi, Patrizia Polverino de laureto, Elisa Lubian, Francesco Selvestrel, Fabrizio Mancin, Emanuele Papini
A coat of strongly-bound host proteins, or hard corona, may influence the biological and pharmacological features of nanotheranostics by altering their cell-interaction selectivity and macrophages clearance. With the goal of...
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