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Friday, November 13, 2015

Specific Detection of the Cleavage Activity of Mycobacterial Enzymes using a Quantum Dots based DNA Nanosensor

Nanoscale, 2015, Accepted Manuscript
DOI: 10.1039/C5NR06326D, Paper
Morten Leth Jepsen, Charlotte Harmsen, Adwait A. Godbole, Valakunja Nagaraja, Birgitta R. Knudsen, Yi-Ping Ho
We present a quantum dot based DNA nanosensor specifically targeting the cleavage step in the reaction cycle of the essential DNA-modifying enzyme, mycobacterial topoisomerase I. The design takes advantages of...
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