Tuesday, July 22, 2014

Tempo-spatially resolved cellular dynamics of human immunodeficiency virus transacting activator of transcription (Tat) peptide-modified nanocargos in living cells




Nanoscale , 2014, Advance Article

DOI: 10.1039/C4NR02732A, Paper

Lin Wei, Qiaoyu Yang, Lehui Xiao

The tempo-spatially resolved dynamics of Tat peptide-functionalized gold nanoparticles (TGNPs) in living HeLa cells revealed that TGNPs could not actively target the cell nuclei and the inheritance of TGNPs to the daughter cells through mitosis was the major route to metabolize TGNPs by HeLa cells.

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