Tuesday, April 14, 2015

Synthesis and application of glycoconjugate-functionalized magnetic nanoparticles as potent anti-adhesion agents for reducing enterotoxigenic Escherichia coli infections

Nanoscale , 2015, Accepted Manuscript

DOI: 10.1039/C5NR00511F, Communication

Yash Raval, Roland Stone, Benjamin Fellows, Bin Qi, Olin Thompson Mefford, Jeremy Tzeng T R

Polyethylene oxide stabilized magnetic nanoparticles (PEO-MNPs) bio-functionalized with glycoconjugate (Neu5Ac([small alpha]2-3)Gal([small beta]1-4)Glc[small beta]-sp) (GM3-MNPs) are synthesized using click chemistry. Interaction of GM3-MNPs with Enterotoxigenic Escherichia coli (ETEC) strain K99 (EC K99) is investigated...

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