Thursday, June 18, 2015

In situ microfluidic SERS assay for monitoring enzymatic breakdown of organophosphates

Nanoscale, 2015, 7,11013-11023
DOI: 10.1039/C5NR01974E, Paper
Vladimir Liberman, Kimberly Hamad-Schifferli, Todd A. Thorsen, Scott T. Wick, Peter A. Carr
In this paper, we report on a method to probe the breakdown of the organophosphate (OP) simulants o,s-diethyl methyl phosphonothioate (OSDMP) and demeton S by the enzyme organophosphorous hydrolase (OPH) in a microfluidic device by surface enhanced Raman spectroscopy (SERS).
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