Thursday, July 23, 2015

Novel stable dendrimersome formulation for safe bioimaging applications

Nanoscale, 2015, 7,12943-12954
DOI: 10.1039/C5NR02695D, Paper
M. Filippi, D. Patrucco, J. Martinelli, M. Botta, P. Castro-Hartmann, L. Tei, E. Terreno
Novel low-generation Janus dendrimers were studied to assess their ability to self-assemble into dendrimersomes and to load the magnetic resonance imaging agent Gadoteridol. Stability and biocompatibility of the nanovesicles were investigated in biological fluids, on cell cultures and in healthy mice.
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