Promoting Effect of Carbon Surfaces on H2 Dissociation on Aln Clusters by First Principles Calculations

The Journal of Physical Chemistry C

DOI: 10.1021/jp410482x

Francesca Costanzo, Marc C. van Hemert and Geert-Jan Kroes

Click for full article

Synthesis and Characterization of Solvothermal Processed Calcium Tungstate Nanomaterials from Alkoxide Precursors

Chemistry of Materials

DOI: 10.1021/cm402622b

Timothy J. Boyle, Pin Yang, Khalid Hattar, Bernadette A. Hernandez-Sanchez, Michael L. Neville and Sarah Hoppe

Click for full article

Optimizing manufacturing and composition of a TLR4 nanosuspension: physicochemical stability and vaccine adjuvant activity

Background: Nanosuspensions are an important class of delivery system for vaccine adjuvants and drugs. Previously, we developed a nanosuspension consisting of the synthetic TLR4 ligand glucopyranosyl lipid adjuvant (GLA) and dipalmitoyl phosphatidylcholine (DPPC). This nanosuspension is a clinical vaccine adjuvant known as GLA-AF. We examined the effects of DPPC supplier, buffer composition, and manufacturing process on GLA-AF physicochemical and biological activity characteristics. Results: DPPC from different suppliers had minimal influence on physicochemical and biological effects. In general, buffered compositions resulted in less particle size stability compared to unbuffered GLA-AF. Microfluidization resulted in rapid particle size reduction after only a few passes, and 20,000 or 30,000 psi processing pressures were more effective at reducing particle size and recovering the active component than 10,000 psi. Sonicated and microfluidized batches maintained good particle size and chemical stability over 6 months, without significantly altering in vitro or in vivo bioactivity of GLA-AF when combined with a recombinant malaria vaccine antigen. Conclusions: Microfluidization, compared to water bath sonication, may be an effective manufacturing process to improve the scalability and reproducibility of GLA-AF as it advances further in the clinical development pathway. Various sources of DPPC are suitable to manufacture GLA-AF, but buffered compositions of GLA-AF do not appear to offer stability advantages over the unbuffered composition.

HW Fung

Click for full article

Visible-Light Photocatalysis in Ca0.6Ho0.4MnO3 Films Deposited by RF-Magnetron Sputtering Using Nanosized Powder Compacted Target

The Journal of Physical Chemistry C

DOI: 10.1021/jp412016a

B. Barrocas, S. Sério, A. Rovisco and M. E. Melo Jorge

Click for full article

A Facile Approach to Construct Multiple Structured ZnO Crystals by Trisodium Citrate-Assisted Hydrothermal Growth Toward Performance Enhancement of Dye-Sensitized Solar Cells

The Journal of Physical Chemistry C

DOI: 10.1021/jp410325p

Shibu Zhu, Xin Tian, Jingjing Chen, Liming Shan, Xiaoling Xu and Zuowan Zhou

Click for full article

Polarons, Compressed Polarons, and Bipolarons in Conjugated Polymers

The Journal of Physical Chemistry C

DOI: 10.1021/jp408910a

Jin Bakalis, Andrew R. Cook, Sadayuki Asaoka, Michael Forster, Ulrich Scherf and John R. Miller

Click for full article

Silicon/Hematite Core/Shell Nanowire Array Decorated with Gold Nanoparticles for Unbiased Solar Water Oxidation

Nano Letters

DOI: 10.1021/nl402205f

Xin Wang, Kui-Qing Peng, Ya Hu, Fu-Qiang Zhang, Bo Hu, Li Li, Meng Wang, Xiang-Min Meng and Shuit-Tong Lee

Click for full article

Influence of the Position of the Side Chain on Crystallization and Solar Cell Performance of DPP-Based Small Molecules

Chemistry of Materials

DOI: 10.1021/cm4034484

Veronique S. Gevaerts, Eva M. Herzig, Mindaugas Kirkus, Koen H. Hendriks, Martijn M. Wienk, Jan Perlich, Peter Müller-Buschbaum and René A. J. Janssen

Click for full article

Vibronic Coupling in the Ground State of Oligoacene Cations: The Performance of Range-Separated Hybrid Density Functionals

The Journal of Physical Chemistry C

DOI: 10.1021/jp4095326

Cai-Rong Zhang, Veaceslav Coropceanu, John S. Sears and Jean-Luc Brédas

Click for full article

Dissociative Adsorption of 5-Nitro-2,4-dihydro-3H-1,2,4-triazol-3-one (NTO) on Aluminum-Terminated (0001) Surface of α-Alumina As Predicted from Plane-Wave Density Functional Theory

The Journal of Physical Chemistry C

DOI: 10.1021/jp408661h

Manoj K. Shukla and Frances Hill

Click for full article

Charge Transport Limitations of Redox Mediators in Dye-Sensitized Solar Cells: Investigation Based on a Quasi-Linear Model

The Journal of Physical Chemistry C

DOI: 10.1021/jp407769s

Hui Wang, Zhe Sun, Yake Zhang, Yue Zhang, Mao Liang, Dongdong Jia and Song Xue

Click for full article

High Activity Redox Catalysts Synthesized by Chemical Vapor Impregnation

ACS Nano

DOI: 10.1021/nn405757q

Michael M. Forde, Lokesh Kesavan, Mohd Izham bin Saiman, Qian He, Nikolaos Dimitratos, Jose Antonio Lopez-Sanchez, Robert L. Jenkins, Stuart H. Taylor, Christopher J. Kiely and Graham J. Hutchings

Click for full article

Tailoring the Resonance of Bilayer Graphene Sheets by Interlayer sp3 Bonds

The Journal of Physical Chemistry C

DOI: 10.1021/jp4109442

H. F. Zhan, Y. Y. Zhang, J. M. Bell, B. C. Zhang and Y. T. Gu

Click for full article

Synthesis and Evaluation of a Nanoglobular Dendrimer 5-Aminosalicylic Acid Conjugate with a Hydrolyzable Schiff Base Spacer for Treating Retinal Degeneration

ACS Nano

DOI: 10.1021/nn4054107

Xueming Wu, Guanping Yu, Chengcai Luo, Akiko Maeda, Ning Zhang, Da Sun, Zhuxian Zhou, Anthony Puntel, Krzysztof Palczewski and Zheng-Rong Lu

Click for full article

Ternary Hybrid Nanoparticle Isomers: Directing the Nucleation of Ag on Pt–Fe3O4 Using a Solid-State Protecting Group

ACS Nano

DOI: 10.1021/nn405943z

James M. Hodges, Adam J. Biacchi and Raymond E. Schaak

Click for full article

Toward Single-Molecule Optical Mapping of the Epigenome

ACS Nano

DOI: 10.1021/nn4050694

Michal Levy-Sakin, Assaf Grunwald, Soohong Kim, Natalie R. Gassman, Anna Gottfried, Josh Antelman, Younggyu Kim, Sam O. Ho, Robin Samuel, Xavier Michalet, Ron R. Lin, Thomas Dertinger, Andrew S. Kim, Sangyoon Chung, Ryan A. Colyer, Elmar Weinhold, Shimon Weiss and Yuval Ebenstein

Click for full article

Long-Range Periodicity of S/Au(111) Structures at Low and Intermediate Coverages

The Journal of Physical Chemistry C

DOI: 10.1021/jp408340d

P. N. Abufager, G. Zampieri, K. Reuter, M. L. Martiarena and H. F. Busnengo

Click for full article

Simple Analytical Equations for the Current–Potential Curves at Microelectrodes: A Universal Approach

The Journal of Physical Chemistry C

DOI: 10.1021/jp409167m

Angela Molina, Joaquin Gonzalez, Edward O. Barnes and Richard G. Compton

Click for full article