Showing posts with label May 11. Show all posts
Showing posts with label May 11. Show all posts

Monday, May 11, 2015

Interaction of Acetonitrile with Water-Ice: An Infrared Spectroscopic Study

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The Journal of Physical Chemistry C
DOI: 10.1021/jp512607v

Radha Gobinda Bhuin, Rabin Rajan J. Methikkalam, Bhalamurugan Sivaraman and Thalappil Pradeep
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Surprisingly High Conductivity and Efficient Exciton Blocking in Fullerene/Wide-Energy-Gap Small Molecule Mixtures

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Nano Letters
DOI: 10.1021/acs.nanolett.5b00908

Kevin J. Bergemann, Jojo A. Amonoo, Byeongseop Song, Peter F. Green and Stephen R. Forrest
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Large Frequency Change with Thickness in Interlayer Breathing ModeSignificant Interlayer Interactions in Few Layer Black Phosphorus

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Nano Letters
DOI: 10.1021/acs.nanolett.5b00775

Xin Luo, Xin Lu, Gavin Kok Wai Koon, Antonio H. Castro Neto, Barbaros Özyilmaz, Qihua Xiong and Su Ying Quek
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Size and Orientation Effects on the Kinetics and Structure of Nickelide Contacts to InGaAs Fin Structures

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Nano Letters
DOI: 10.1021/acs.nanolett.5b00327

Renjie Chen and Shadi A. Dayeh
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Hierarchical Graphene/Metal Grid Structures for Stable, Flexible Transparent Conductors

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ACS Nano
DOI: 10.1021/acsnano.5b01243

Tongchuan Gao, Zhiting Li, Po-shun Huang, Ganesh J. Shenoy, David Parobek, Susheng Tan, Jung-kun Lee, Haitao Liu and Paul W. Leu
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Conductive Atomic Force Microscopy Investigation of Switching Thresholds in Titanium Dioxide Thin Films

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The Journal of Physical Chemistry C
DOI: 10.1021/acs.jpcc.5b01672

M. Trapatseli, D. Carta, A. Regoutz, A. Khiat, A. Serb, I. Gupta and T. Prodromakis
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Coverage Dependent Water Dissociative Adsorption on the Clean and O-Precovered Fe(111) Surfaces

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The Journal of Physical Chemistry C
DOI: 10.1021/acs.jpcc.5b02297

Shaoli Liu, Xinxin Tian, Tao Wang, Xiaodong Wen, Yong-Wang Li, Jianguo Wang and Haijun Jiao
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Hidden Dityrosine Residues in Protein-Protected Gold Nanoclusters

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The Journal of Physical Chemistry C
DOI: 10.1021/acs.jpcc.5b03224

Lei Su, Tong Shu, Jianxing Wang, Zhenyun Zhang and Xueji Zhang
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Efficient All-Printable Solid-State Dye-Sensitized Solar Cell Based on a Low-Resistivity Carbon Composite Counter Electrode and Highly Doped Hole Transport Material

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The Journal of Physical Chemistry C
DOI: 10.1021/acs.jpcc.5b01711

Timothy W. Jones, Noel W. Duffy and Gregory J. Wilson
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One-Dimensional Oxygen Diffusion Mechanism in Sr2ScGaO5 Electrolyte Explored by Neutron and Synchrotron Diffraction, 17O NMR, and Density Functional Theory Calculations

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The Journal of Physical Chemistry C
DOI: 10.1021/acs.jpcc.5b02173

Serena Corallini, Monica Ceretti, Gilles Silly, Andrea Piovano, Shubra Singh, Josef Stern, Clemens Ritter, Jinjun Ren, Hellmut Eckert, Kazimirz Conder, Wei-tin Chen, Fang-Cheng Chou, Noriya Ichikawa, Yuichi Shimakawa and Werner Paulus
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Density Functional Theory Study of Adsorption of Benzotriazole on Cu2O Surfaces

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The Journal of Physical Chemistry C
DOI: 10.1021/acs.jpcc.5b01677

Anton Kokalj and Sebastijan Peljhan
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Monday, May 12, 2014

Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells

Background: In hepatocellular carcinoma (HCC), different signaling pathways are de-regulated, and among them, the expression of the epidermal growth factor receptor (EGFR). Tyrphostin AG-1478 is a lipophilic low molecular weight inhibitor of EGFR, preferentially acting on liver tumor cells. In order to overcome its poor drug solubility and thus improving its anticancer activity, it was entrapped into nanostructured lipid carriers (NLC) by using safe ingredients for parenteral delivery. Results: Nanostructured lipid carriers (NLC) carrying tyrphostin AG-1478 were prepared by using the nanoprecipitation method and different matrix compositions. The best system in terms of mean size, PDI, zeta potential, drug loading and release profile was chosen to evaluate the anti-proliferative effect of drug-loaded NLC versus free drug on human hepatocellular carcinoma HA22T/VGH cells. Conclusions: Thanks to the entrapment into NLC systems, tyrphostin AG-1478 shows an enhanced in vitro anti-tumor activity compared to free drug. These finding raises hope of future drug delivery strategy of tyrphostin AG-1478 -loaded NLC targeted to the liver for the HCC treatment.

Maria Bondì

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Interfacial film stabilized W/O/W nano multiple emulsions loaded with green tea and lotus extracts: systematic characterization of physicochemical properties and shelf-storage stability

Background and aims: Multiple emulsions have excellent encapsulating potential and this investigation has been aimed to encapsulate two different plant extracts as functional cosmetic agents in the W/O/W multiple emulsions and the resultant system's long term stability has been determined in the presence of a thickener, hydroxypropyl methylcellulose (HPMC). Methods: Multiple W/O/W emulsions have been generated using cetyl dimethicone copolyol as lipophilic emulsifier and a blend of polyoxyethylene (20) cetyl ether and cetomacrogol 1000(R) as hydrophilic emulsifiers. The generated multiple emulsions have been characterized with conductivity, pH, microscopic analysis, phase separation and rheology for a period of 30 days. Moreover, long term shelf-storage stability has been tested to understand the shelf-life by keeping the generated multiple emulsion formulations at 25 +/- 10[degree sign]C and at 40 +/- 10% relative humidity for a period of 12 months. Results: It has been observed that the hydrophilic emulsifiers and HPMC have considerably improved the stability of multiple emulsions for the followed period of 12 months at different storage conditions. These multiple emulsions have shown improved entrapment efficiencies concluded on the release rate of conductometric tracer entrapped in the inner aqueous phase of the multiple emulsions. Conclusion: Multiple emulsions have been found to be stable for a longer period of time with promising characteristics. Hence, stable multiple emulsions loaded with green tea and lotus extracts could be explored for their cosmetic benefits.

Tariq Mahmood

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