Monday, March 17, 2014

Structure, mechanics, and binding mode heterogeneity of LEDGF/p75-DNA nucleoprotein complexes revealed by scanning force microscopy




Nanoscale , 2014, Advance Article

DOI: 10.1039/C4NR00022F, Paper

Willem Vanderlinden, Jan Lipfert, Jonas Demeulemeester, Zeger Debyser, Steven De Feyter

SFM imaging reveals that LEDGF/p75 alters the DNA structure and mechanics through bridging, unwinding and the formation of flexible bends.

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