Real-time, non-invasive monitoring of hydrogel degradation using LiYF4:Yb3+/Tm3+ NIR-to-NIR upconverting nanoparticles

Nanoscale, 2015, 7,11255-11262
DOI: 10.1039/C5NR02482J, Communication

Ghulam Jalani, Rafik Naccache, Derek H. Rosenzweig, Sophie Lerouge, Lisbet Haglund, Fiorenzo Vetrone, Marta Cerruti
LiYF₄:Yb³⁺/Tm³⁺ upconverting nanoparticles are used for real-time tracking of degradation of chitosan-hyaluronic acid gels in live intervertebral discs using photoluminescence spectroscopy and NIR imaging.
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