Friday, December 25, 2015

Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo

Nanoscale, 2015, Accepted Manuscript
DOI: 10.1039/C5NR06162H, Paper
Avik Som, Ramesh Raliya, Limei Tian, Walter Akers, Joseph Ippolito, Srikanth Singamaneni, Pratim Biswas, Samuel Achilefu
The acidic extracellular environment of tumors potentiates their aggressiveness and metastasis, but few methods exist to selectively modulate the extracellular pH (pHe) environment of tumors. Transient flushing of biological systems...
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