Tuesday, October 29, 2013

Biodegradable polymeric micelle-encapsulated quercetin suppresses tumor growth and metastasis in both transgenic zebrafish and mouse models




Nanoscale , 2013, Advance Article

DOI: 10.1039/C3NR04651F, Paper

Qinjie Wu, Senyi Deng, Ling Li, Lu Sun, Xi Yang, Xinyu Liu, Lei Liu, Zhiyong Qian, Yuquan Wei, Changyang Gong

Quercetin loaded polymeric micelles (Que micelles) were prepared to obtain an aqueous formulation of quercetin. Stronger inhibitory effects of Que micelles were observed on angiogenesis, growth, and metastasis of tumors in transgenic zebrafish models and mouse model.

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