Wednesday, April 30, 2014

Optimizing the selective recognition of protein isoforms through tuning of nanoparticle hydrophobicity

Nanoscale , 2014, Accepted Manuscript

DOI: 10.1039/C4NR01085J, Communication

kaimin chen, Subinoy Rana, Daniel Moyano, Yisheng Xu, Xuhong Guo, Vincent M Rotello

We demonstrate that ligand hydrophobicity can be used to increase affinity and selectivity of binding between monolayer-protected cationic gold nanoparticles and [small beta]-lactoglobulin protein isoforms containing two amino acid mutations.

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