Monday, November 09, 2015

Theranostic reduction-sensitive gemcitabine prodrug micelles for near-infrared imaging and pancreatic cancer therapy

Nanoscale, 2015, Accepted Manuscript
DOI: 10.1039/C5NR06734K, Paper
Haijie Han, Haibo Wang, Yangjun Chen, Zuhong Li, Yin Wang, Qiao Jin, Jian Ji
A biodegradable and reduction-cleavable gemcitabine (GEM) polymeric prodrug with in vivo near-infrared (NIR) imaging ability was reported. The theranostic GEM prodrug PEG-b-[PLA-co-PMAC-graft-(IR820-co-GEM)] was synthesized by ring-opening polymerization (ROP) and "click"...
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