Tuesday, January 19, 2016

A highly fluorescent AIE-active theranostic agent with anti-tumor activity to specific cancer cells

Nanoscale, 2016, Advance Article
DOI: 10.1039/C5NR08782A, Communication
Yueyue Zhao, Ryan T. K. Kwok, Jacky W. Y. Lam, Ben Zhong Tang
A tetraphenylethene derivative with a structure resembling Tamoxifen is synthesized as a theranostic agent for cell imaging and anti-breast cancer therapy. Its high brightness, excellent photostability and long-term cell tracing properties enable elucidation of its working mechanism and hence provide new insights into drug development.
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