Thursday, March 26, 2015

Polyhydroxylated [60]fullerene binds specifically to functional recognition sites on a monomeric and a dimeric ubiquitin




Nanoscale , 2015, Advance Article

DOI: 10.1039/C5NR00539F, Paper

Serena Zanzoni, Alberto Ceccon, Michael Assfalg, Rajesh K. Singh, David Fushman, Mariapina D'Onofrio

Fullerenol binds specifically to a functional surface patch on ubiquitin, thereby preventing chain formation. The nanoparticle also interacts with a covalent ubiquitin dimer, targeting a physiological recognition site.

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