Thursday, February 26, 2015

Ligand-functionalized degradable polyplexes formed by cationic poly(aspartic acid)s-grafted chitosan-cyclodextrin conjugates

Nanoscale , 2015, Accepted Manuscript

DOI: 10.1039/C4NR07515C, Paper

Hai-Qing Song, Quiquan Li, Shun Duan, BR Yu, Hong Zhao, Dafu Chen, F.J. Xu

Polypeptide-based degradable polyplexes attracted considerable attention in drug delivery systems. Polysaccharides including cyclodextrin (CD), dextran, and chitosan (CS) were readily grafted with cationic poly(aspartic acid)s (PAsps). To further enhance the...

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