Ultra-High-Density 3D DNA Arrays within Nanoporous Biocompatible Membranes for Single-Molecule-Level Detection and Purification of Circulating Nucleic Acids

Nanoscale , 2015, Accepted Manuscript

DOI: 10.1039/C4NR07351G, Paper

Morteza Aramesh, Olga Shimoni, Kate Fox, Timothy Karle, Alexander Lohrmann, Kostya Ostrikov, Steven Prawer, Jiri Cervenka

Extracellular nucleic acids freely circulating in blood and other physiologic fluids are important biomarkers for non-invasive diagnostics and early detection of cancer and other diseases, yet difficult to detect because...

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