Thursday, February 26, 2015

Size-dependent tuning of horseradish peroxidase bioreactivity by gold nanoparticles




Nanoscale , 2015, 7,4505-4513

DOI: 10.1039/C4NR07056A, Paper

Haohao Wu, Yi Liu, Meng Li, Yu Chong, Mingyong Zeng, Y. Martin Lo, Jun-Jie Yin

Here we report gold nanoparticles can size-dependently enhance or inhibit HRP bioreactivity toward substrates with different redox potentials via a mechanism involving extension of the HRP substrate access channel and decline in the redox potentials of HRP catalytic intermediates.

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