Au nanorings (NRIs), which have the localized surface plasmon resonance (LSPR) wavelength around 1058 nm, either with or without linked antibodies, are applied to SAS oral cancer cells for cell inactivation through the LSPR-induced photothermal effect when they are illuminated by a laser of 1065 nm in wavelength. Different incubation times of cells with Au NRIs are considered for observing the variations of cell uptake efficiency of Au NRI and the threshold laser intensity for cell inactivation. In each case of incubation time, the cell sample is washed for evaluating the total Au NRI number per cell adsorbed and internalized by the cells based on inductively coupled plasma mass spectrometry measurement. Also, the Au NRIs remaining on cell membrane are etched with KI/I 2 solution to evaluate the internalized Au NRI number per cell. The threshold laser intensities for cell inactivation before washout, after washout, and after KI/I 2 etching are calibrated from ...
Che-Kuan Chu, Yi-Chou Tu, Yu-Wei Chang, Chih-Ken Chu, Shih-Yang Chen, Ting-Ta Chi, Yean-Woei Kiang and Chih-Chung Yang
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Che-Kuan Chu, Yi-Chou Tu, Yu-Wei Chang, Chih-Ken Chu, Shih-Yang Chen, Ting-Ta Chi, Yean-Woei Kiang and Chih-Chung Yang
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