Tuesday, September 24, 2013

Nanostructured TiO2 surfaces promote polarized activation of microglia, but not astrocytes, toward a proinflammatory profile




Nanoscale , 2013, Advance Article

DOI: 10.1039/C3NR03534D, Paper

Silvia De Astis, Irene Corradini, Raffaella Morini, Simona Rodighiero, Romana Tomasoni, Cristina Lenardi, Claudia Verderio, Paolo Milani, Michela Matteoli

Nanostructured substrates are able, exclusively in virtue of their physical properties and depending on the graded nanoscale rugosity, to push microglia toward a proinflammatory activation phenotype.

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