Monday, June 02, 2014

DNA and aptamer stabilized gold nanoparticles for targeted delivery of anticancer therapeutics




Nanoscale , 2014, Advance Article

DOI: 10.1039/C4NR00019F, Paper

Alfonso Latorre, Christian Posch, Yolanda Garcimartin, Anna Celli, Martina Sanlorenzo, Igor Vujic, Jeffrey Ma, Mitchell Zekhtser, Klemens Rappersberger, Susana Ortiz-Urda, Alvaro Somoza

Aptamer modified gold nanoparticles target malignant cells. Anti-cancer therapeutics are released after cleavage of a self-immolative linker by intracellular triggers.

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