Wednesday, August 07, 2013

Direct observation of a single nanoparticle-ubiquitin corona formation




Nanoscale , 2013, Advance Article

DOI: 10.1039/C3NR02147E, Paper

Feng Ding, Slaven Radic, Ran Chen, Pengyu Chen, Nicholas K. Geitner, Jared M. Brown, Pu Chun Ke

Ubiquitin binds to the silver nanoparticle via specific interactions, where a small subset of protein residues makes contact with the surface atoms of the nanoparticle. Under a high protein/nanoparticle stoichiometry, ubiquitins formed a multi-layer corona on the particle surface.

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