Thursday, August 08, 2013

Structural and Energetic Basis for Hybridization Limits in High-Density DNA Monolayers

Nanoscale , 2013, Accepted Manuscript

DOI: 10.1039/C3NR01799K, Paper

Giovanni Doni, Maryse Nkoua Ngavouka, Alessandro Barducci, Pietro Parisse, Alessandro De Vita, G Scoles, Loredana Casalis, Giovanni M. Pavan

Molecular dynamics simulations of high-density DNA monolayer systems with variable hybridization reveal that, independently on other experimental parameters, hybridization is intrinsically limited by molecular and electrostatic crowding.

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